Relationship between response to lusutrombopag and splenic volume

Table 2 Univariate and multivariate analyses of factors affecting the response to lusutrombopag

	Univariate analysis			Multiple analysis
Variable		OR (95%CI)	P value	OR (95%CI)	P value
Splenic size (mL)	1: < 723	13.5 (1.556-117.1)	0.018	11.2 (1.354-103.0)	0.025
	2: ≥ 723
Gender	1: Male
	2: Female	5.41 (0.621-40.95)	0.368
Age (yr)	1: <69	1.11 (0.270-4.550)	0.168
	2: ≥ 69
Platelets (×104/μL)	1: < 4.5
	2: ≥ 4.5	2.02 (0.442-9.412)	0.212
Hemoglobin (g/dL)	1: < 12.4
	2: ≥ 12.4	2.581 (0.582-11.42)	0.212
BUN (mg/dL)	1: < 15.2	1.66 (0.405-9.412)	0.190
	2: ≥ 15.2
Child-Pugh	1: < 7	1.56 (0.582-11.42)	0.212
	2: ≥ 7
White blood cells (/μl)	1: < 3000
	2: ≥ 3000	4.70 (0.878-25.22)	0.072
Weight (kg)	1: < 62	2.85 (0.643-12.64)	0.168
	2: ≥ 62
Ammonia (μg/dL)	1: < 56.5	1.43 (0.347-5.851)	0.623
	2: ≥ 56.5