Retrospective Study
Copyright ©The Author(s) 2018.
World J Gastroenterol. Nov 14, 2018; 24(42): 4809-4820
Published online Nov 14, 2018. doi: 10.3748/wjg.v24.i42.4809
Table 4 Relationships of tumor grade and invasion depth with tissue architecture n (%)
Tumor grade
Invasion depth
VariableAdenoma(n = 81)Cancer1(n = 49)P valueSM invasion depth ≥ 1000 μm (n = 49)SM invasion depth < 1000 μm (n = 31)P value
Lining epithelium degeneration/prolapseAbsent69 (85.2)20 (40.8)20 (40.8)1 (3.2)
Present12 (14.8)29 (59.2)< 0.000129 (59.2)30 (96.8)0.001
Irregularity in glandular duct size/arrangementAbsent54 (66.7)10 (20.4)10 (20.4)1 (3.2)
Present27 (33.3)39 (79.6)< 0.000139 (79.6)25 (80.6)0.113
Superficial differentiationWell-diff.42 (85.7)42 (85.7)20 (64.5)
Moderately diff.7 (14.3)7 (14.3)10 (32.3)
Poorly diff.0 (0.0)0 (0.0)1 (3.2)0.027
Superficial desmoplastic reactionAbsent81 (100)47 (95.9)47 (95.9)17 (54.8)
Present0 (0.0)2 (4.1)0.2732 (4.1)14 (45.2)< 0.0001
Loss of muscularis mucosaeAbsent0 (0.0)3 (6.1)3 (6.1)29 (93.5)
Present81 (100)46 (93.9)0.09946 (93.9)2 (6.5)< 0.0001
Granuloma formationAbsent80 (98.8)44 (89.8)44 (89.8)19 (61.3)
Present1 (1.2)5 (10.2)0.0545 (10.2)2 (38.7)0.002