Second primary malignancy risk after radiotherapy in rectal cancer survivors

Table 2 Second primary malignancy of different treatment groups

	All patients	Surgery-only	Long	Short	Post
All SPM	1270 (100)	1056 (100)	49 (100)	10 (100)	155 (100)
Head and neck	89 (7)	69 (6.5)	7 (14.3)	2 (20)	11 (7.1)
Esophagus	31 (2.4)	28 (2.7)	0 (0)	0 (0)	3 (1.9)
Stomach	82 (6.5)	68 (6.4)	4 (8.2)	1 (10)	9 (5.8)
Liver	183 (14.4)	162 (15.3)	3 (6.1)	3 (30)	15 (9.7)
Pancreas	31 (2.4)	26 (2.5)	1 (2)	0 (0)	4 (2.6)
Lung	284 (22.4)	224 (21.2)	16 (32.7)	0 (0)	44 (28.4)
Bone	17 (1.3)	14 (1.3)	0 (0)	0 (0)	3 (1.9)
Skin	31 (2.4)	23 (2.2)	1 (2)	2 (20)	5 (3.2)
Breast	82 (6.5)	71 (6.7)	3 (6.1)	0 (0)	8 (5.2)
Cervix	18 (1.4)	17 (1.6)	0 (0)	0 (0)	1 (0.6)
Uterus	15 (1.2)	10 (0.9)	2 (4.1)	0 (0)	3 (1.9)
Ovary	10 (0.8)	10 (0.9)	0 (0)	0 (0)	0 (0)
Prostate	129 (10.2)	116 (11)	2 (4.1)	1 (10)	10 (6.5)
Bladder	83 (6.5)	63 (6)	2 (4.1)	0 (0)	18 (11.6)
Kidney	45 (3.5)	40 (3.8)	1 (2)	1 (10)	3 (1.9)
Thyroid	18 (1.4)	15 (1.4)	0 (0)	0 (0)	3 (1.9)
Hematologic	59 (4.6)	46 (4.4)	3 (6.1)	0 (0)	10 (6.5)
Others	63 (5)	54 (5.1)	4 (8.2)	0 (0)	5 (3.2)

SPM: Second primary malignancy.