Postoperative survival analysis and prognostic nomogram model for patients with portal hypertension

Table 2 Univariate Cox regression analysis of overall survival, bleeding-free survival and disease-specific survival

Parameter	OS				BFS				DSS
	B	P value	RR	95%CI	B	P value	RR	95%CI	B	P value	RR	95%CI
Type of operation	0.16	0.62	1.18	0.62-2.23	-0.39	0.33	0.68	0.31-1.48	-0.45	0.17	0.64	0.34-1.21
CCI	0.04	0.00	1.04	1.01-1.07	0.02	0.36	1.02	0.98-1.05	0.06	0.00	1.06	1.02-1.09
Gender	0.01	0.99	1.01	0.54-1.89	0.94	0.02	2.56	1.20-5.43	0.06	0.91	1.06	0.43-2.60
Age	0.06	0.00	1.06	1.03-1.09	0.04	0.01	1.05	1.01-1.08	0.05	0.00	1.05	1.02-1.09
Aetiology	0.07	0.74	1.07	0.73-1.56	0.16	0.44	1.18	0.78-1.78	-0.16	0.43	0.86	0.58-1.26
History of variceal ligation	0.75	0.10	2.12	0.87-5.19	1.07	0.01	2.92	1.24-6.88	0.54	0.21	1.72	0.73-4.02
History of abdominal surgery	0.33	0.42	1.39	0.63-3.03	0.16	0.73	1.17	0.48-2.87	-1.28	0.20	0.28	0.04-1.96
Smoking	0.45	0.19	1.56	0.80-3.04	0.54	0.15	1.72	0.82-3.60	0.27	0.55	1.31	0.55-3.11
Drinking	0.17	0.65	1.19	0.56-2.51	0.71	0.07	2.04	0.96-4.33	-0.12	0.81	0.89	0.34-2.35
Charlson Score	0.11	0.53	1.12	0.80-1.56	0.02	0.93	1.02	0.69-1.51	0.06	0.77	1.06	0.72-1.58
History of variceal bleeding	0.07	0.82	1.08	0.57-2.03	1.02	0.01	2.77	1.30-5.90	-0.30	0.43	0.74	0.36-1.55
Blood type	-0.20	0.25	0.82	0.58-1.15	-0.15	0.41	0.86	0.60-1.23	-0.16	0.29	0.85	0.63-1.15
BMI	-0.06	0.34	0.94	0.83-1.07	0.00	0.97	1.00	0.88-1.14	-0.03	0.57	0.97	0.86-1.09
Total hospital stay	0.01	0.36	1.01	0.99-1.04	0.00	0.79	1.00	0.98-1.03	-0.03	0.26	0.97	0.93-1.02
Duration of preoperative hospital stay	0.01	0.43	1.01	0.98-1.05	0.01	0.59	1.01	0.97-1.05	0.04	0.20	1.04	0.98-1.09
Duration of postoperative hospital stay	0.03	0.20	1.03	0.98-1.09	-0.01	0.71	0.99	0.92-1.06	0.00	0.91	1.00	0.94-1.08
Operative time	0.01	0.00	1.01	1.00-1.02	0.01	0.04	1.01	1.00-1.02	0.00	0.33	1.00	1.00-1.01
Intraoperative blood loss	0.00	0.01	1.00	1.00-1.01	0.00	0.00	1.00	1.00-1.01	0.00	0.09	1.00	1.00-1.00
Time to first flatus	-0.01	0.94	0.99	0.81-1.21	0.23	0.03	1.26	1.03-1.53	-0.06	0.57	0.94	0.78-1.15
WBC count	0.20	0.03	1.22	1.02-1.45	0.15	0.13	1.16	0.96-1.41	-0.02	0.88	0.98	0.80-1.21
Hb	-0.01	0.04	0.99	0.97-1.00	-0.02	0.04	0.99	0.97-1	-0.01	0.31	0.99	0.97-1.01
Platelet count	0.01	0.08	1.01	1.00-1.02	0.01	0.01	1.01	1.00-1.02	0.01	0.05	1.01	1.00-1.03
PT	0.07	0.46	1.07	0.90-1.27	-0.08	0.44	0.92	0.74-1.14	-0.26	0.75	0.77	0.16-3.66
INR	-0.03	0.93	0.97	0.51-1.83	-0.93	0.44	0.39	0.04-4.29	-1.80	0.84	0.17	0.00-9821579.13
TBIL	0.01	0.22	1.01	0.99-1.03	-0.01	0.45	0.99	0.97-1.02	0.00	0.97	1.00	0.96-1.04
DBIL	0.02	0.20	1.02	0.99-1.06	-0.03	0.34	0.97	0.92-1.03	0.02	0.72	1.02	0.93-1.12
ALT	0.00	0.00	1.00	1.00-1.01	-0.01	0.35	0.99	0.98-1.01	0.01	0.12	1.02	1.00-1.03
AST	0.00	0.01	1.00	1.00-1.01	-0.02	0.10	0.98	0.96-1.00	-0.01	0.27	0.99	0.97-1.01
ALB	-0.11	0.00	0.90	0.84-0.96	-0.03	0.45	0.98	0.91-1.04	-0.39	0.25	0.68	0.35-1.31
GLB	0.02	0.53	1.02	0.96-1.07	-0.07	0.04	0.93	0.87-1.00	0.03	0.28	1.03	0.97-1.10
Scr	0.01	0.32	1.01	0.99-1.03	0.02	0.07	1.02	1.00-1.03	-0.08	0.01	0.93	0.87-0.98
Cys C	0.71	0.09	2.03	0.91-4.57	0.23	0.67	1.26	0.44-3.66	1.17	0.02	3.21	1.20-8.62
Child-Pugh score	0.29	0.01	1.33	1.08-1.65	0.13	0.36	1.13	0.87-1.48	0.14	0.54	1.15	0.74-1.81
MELD score	0.50	0.18	1.64	0.80-3.40	0.02	0.97	1.02	0.44-2.36	4.18	0.05	65.31	0.94-4536.32
ALBI score	1.07	0.00	2.92	1.49-5.76	0.19	0.59	1.21	0.60-2.46	-3.86	0.33	0.02	0.00-48.67

OS: Overall survival; BFS: Bleeding-free survival; CCI: Comprehensive Complication Index; BMI: Body mass index; WBC: White blood cell; Hb: Haemoglobin; PT: Prothrombin time; INR: International normalised ratio; TBIL: Total bilirubin; DBIL: Direct bilirubin; ALT: Alanine transaminase; AST: Aspartate transaminase; ALB: Albumin; GLB: Globulin; Scr: Serum creatinine; Cys C: Cystatin C; MELD: Model for end-stage liver disease; ALBI: Albumin-bilirubin; B: Regression coefficient; SE: Standard error; RR: Relative risk; CI: Confidence interval.