Carcinogenesis on the background of liver fibrosis: Implications for the management of hepatocellular cancer

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 21, 2018; 24(39): 4436-4447
Published online Oct 21, 2018. doi: 10.3748/wjg.v24.i39.4436

Table 1 Conditions which have been associated with hepatocellular carcinoma development in the non-cirrhotic liver[6,7]

Viral	HBV
Metabolic	Porphyria
	Type 1 glycogen storage disease
	NAFLD
	Α1 antitrypsin
	Haemochromatosis
	Type 1 hypercitrullinemia
Genotoxins	Aflatoxin B1
Congenital	Alagille syndrome
Congenital	Congenital hepatic fibrosis
Sex hormones	Anabolic steroids
Sex hormones	Hepatic adenoma transformation
Vascular	Hepatic vascular pathology, e.g., Budd Chiari

HBV: Hepatitis B virus; NAFLD: Non-alcoholic fatty liver disease.

Citation: O’Rourke JM, Sagar VM, Shah T, Shetty S. Carcinogenesis on the background of liver fibrosis: Implications for the management of hepatocellular cancer. World J Gastroenterol 2018; 24(39): 4436-4447
URL: https://www.wjgnet.com/1007-9327/full/v24/i39/4436.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i39.4436

O’Rourke JM, Sagar VM, Shah T, Shetty S. Carcinogenesis on the background of liver fibrosis: Implications for the management of hepatocellular cancer. World J Gastroenterol 2018; 24(39): 4436-4447 [PMID: 30357021 DOI: 10.3748/wjg.v24.i39.4436]

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