Liver stiffness reversibly increases during pregnancy and independently predicts preeclampsia

Figure 3 Liver stiffness in women without pregnancy complications and a measurement in the third trimester compared to liver stiffness in women with preeclampsia and intrahepatic cholestasis of pregnancy. LS is significantly higher in preeclampsia (17.9 ± 20.7 kPa, P < 0.0001) and cholestasis (6.9 ± 2.1 kPa, P < 0.0001) even when compared to controls in the third trimester (6.0 ± 2.3 kPa), where LS increases also in uncomplicated pregnancies. Two women with preeclampsia had LS measurements of 75 kPa, which are not shown for design reasons. LS: Liver stiffness; ICP: Intrahepatic cholestasis of pregnancy.