Adiponectin affects the mechanical responses in strips from the mouse gastric fundus

Figure 2 Effects of adiponectin on the neurally-induced relaxant responses in strips from the mouse gastric fundus. A: Typical tracing showing the relaxant responses to EFS (left hand panel). ADPN (20 nmol/L) increases the amplitude of the neurally-induced relaxant responses (right hand panel); B: Bar chart showing the influence of ADPN on the mean amplitude of the EFS-induced relaxant responses. Note that ADPN increases the amplitude of the neurally-induced relaxation in the whole range of stimulation frequency employed. Relaxant responses are expressed as percentage decrease relative to the muscular tension induced by 1 μmol/L CCh just before obtaining relaxations. All values are means ± SE of 6 strips from 3 mice. ^aP < 0.05 vs the control (Student's t-test). ADPN: Adiponectin.