Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line

doi:10.3748/wjg.v24.i33.3749

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 7, 2018; 24(33): 3749-3759
Published online Sep 7, 2018. doi: 10.3748/wjg.v24.i33.3749

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Figure 6 Expression of p53 and some of its targets in HROC57 cells. Western Blot analysis of untreated HROC57 cells compared to HCT116 (p53 wildtype) and HCT116 p53^-/- was performed. Acetylation (K382) and phosphorylation (S15) of p53 (A) and expression of its targets p21, survivin and HDAC 1 and 2 (B) were assessed using specific antibodies. HSP90 served as loading control. Numbers indicate densitometric analysis of respective signals normalized to loading control and relative to HCT116 cells.

Citation: Gock M, Mullins CS, Harnack C, Prall F, Ramer R, Göder A, Krämer OH, Klar E, Linnebacher M. Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line. World J Gastroenterol 2018; 24(33): 3749-3759
URL: https://www.wjgnet.com/1007-9327/full/v24/i33/3749.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i33.3749

Gock M, Mullins CS, Harnack C, Prall F, Ramer R, Göder A, Krämer OH, Klar E, Linnebacher M. Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line. World J Gastroenterol 2018; 24(33): 3749-3759 [PMID: 30197480 DOI: 10.3748/wjg.v24.i33.3749]

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