Basic Study
Copyright ©The Author(s) 2018.
World J Gastroenterol. Sep 7, 2018; 24(33): 3749-3759
Published online Sep 7, 2018. doi: 10.3748/wjg.v24.i33.3749
Table 2 Measured IC50 values and selected human plasma reference levels of analyzed chemotherapeutic agents
DrugIC50Plasma reference
5-FU10.53 μg/mL50 μg/mL[44]
SAHA0.249 μg/mL
Oxaliplatin701 ηg/mL2 μg/mL[45]
Folfox5.48 μg/mL + 137.1 ηg/mL
Irinotecan0.745 μg/mL1 μg/mL[46]
Folfiri1 μg/mL + 0.674 μg/mL
Rapamycin4.8 μg/mL5-100 mg/L[47]