Novel sericin-based hepatocyte serum-free medium and sericin’s effect on hepatocyte transcriptome

Figure 3 Relative expression of genes related to hepatocyte function. A: UGT; B: GST; C: GLUL; D: G6P; E: albumin; F: CPS1; G: CYP3A4; and H: CYP2D6 in each group. (group a) Serum-free medium, (group b) HepatoZYME, (group c) DMEM/F12 with 100 mL/L FBS, (group d) DMEM/F12. Data are expressed as mean ± SD (n = 3). ^eP < 0.05, significant difference from group a at the same incubation time. UGT: Uridinediphosphate-glucuronosyl transferase; GLUL: Glutamate-ammonia ligase; CPS1: Carbamoyl phosphate synthetase I; G6P: Glucose-6-phosphatase; CYP3A4: Cytochrome P3A4; CYP2D: Cytochrome P2D6; FBS: Fetal bovine serum.