Fatigue is not associated with vitamin D deficiency in inflammatory bowel disease patients

Table 2 Univariate and multivariate analysis of total fatigue and selected variables in ulcerative colitis (n = 178)

	Univariate B	95%CI	P value	Multivariate B	95%CI	P value
Age	-0.07	-0.13, -0.01	0.03	-0.05	-0.10, 0.00	0.04
Sex (ref. male)	2.30	0.80, 3.80	< 0.01	1.29	0.01, 2.57	0.05
25-OH-D < 50 nmol/L	Ref.
25-OH-D 50-75	-0.27	-1.92, 1.39	0.75
25-OH-D > 75	-0.93	-3.33, 1.47	0.45
SCCAI ≥ 5	5.66	4.20, 7.12	< 0.01	4.25	2.75, 5.75	< 0.01
CRP ≥ 5 mg/L	0.35	-1.37, 2.07	0.69
Calprotectin ≥ 100 mg/kg	0.61	-1.18, 2.40	0.50
Depressive symptoms1	4.78	2.68, 6.88	< 0.01	2.37	0.44, 4.30	0.02
Sleep disturbance	4.17	2.50, 5.84	< 0.01	2.07	0.47, 3.67	0.01

¹HADS: Hospital Anxiety and depression score - depression subscore ≥ 8. UC: Ulcerative colitis; SCCAI: Simple Clinical Colitis Activity Index; CRP: C-reactive protein; B: Regression coefficient.