Prognostic significance of the fibrinogen-to-albumin ratio in gallbladder cancer patients

Table 5 Univariate analysis of overall survival in gallbladder cancer patients

Characteristics	HR (95%CI)	P value
Age (yr)	1.473 (0.973-2.230)	0.067
≤ 60
> 60
Sex	0.995 (0.670-1.477)	0.981
Male
Female
Cholecystolithiasis	1.198 (0.814-1.764)	0.360
Absent
Present
Diabetes	1.028 (0.651-1.623)	0.906
Absent
Present
Jaundice	2.598 (1.644-4.106)	< 0.001
Absent
Present
Blood groups	-	0.113
A
B
AB
O
Pathological types	-	0.165
Adenosquamous carcinoma
Adenocarcinoma
Papillocarcinoma
Degree of differentiation	1.527 (1.031-2.261)	0.035
Poor
Moderate-well
Resection margin status	3.683 (2.468-5.496)	< 0.001
Negative
Positive
Maximum tumor diameter (cm)	1.101 (0.744-1.630)	0.631
≤ 2.45
> 2.45
T stage	-	< 0.001
Tis-T1a
T1b-T2b
T3
T4
N stage	-	< 0.001
0
1
2
Distant metastasis	2.550 (1.388-4.684)	0.003
Absent
Present
TNM stage	-	< 0.001
0-Istage
IIA-IIB stage
IIIA-IIIB stage
IVA-IVB stage
CA199 (U/mL)	3.125 (2.010-4.858)	< 0.001
≤ 39
> 39
Fibrinogen concentration (g/L)	2.795 (1.853-4.214)	< 0.001
≤ 3.47
> 3.47
Albumin levels (g/L)	0.391(0.259-0.590)	< 0.001
≤ 40.5
> 40.5
FAR	4.626(2.987-7.165)	< 0.001
≤ 0.08
> 0.08

FAR: Fibrinogen to albumin ratio; HR: Hazard ratio; CI: Confidence interval.