Prognostic significance of the fibrinogen-to-albumin ratio in gallbladder cancer patients

Table 3 Correlation between albumin levels and clinicopathological characteristics in gallbladder cancer patients n (%)

Characteristics	Albumin levels		P value
	≤ 40.5g/L(n = 76)	> 40.5 g/L(n = 78)
Age (yr)
≤ 60	22 (14.3)	34 (22.1)	0.067
> 60	54 (35.1)	44 (28.6)
Sex
Male	28 (18.2)	35 (22.7)	0.330
Female	48 (31.2)	43 (27.9)
Cholecystolithiasis
Absent	34 (22.1)	45 (29.2)	0.147
Present	42 (27.3)	33 (21.4)
Diabetes
Absent	53 (34.4)	63 (40.9)	0.136
Present	23 (14.9)	15 (9.7)
Jaundice
Absent	54 (35.1)	75 (48.7)	< 0.001
Present	22 (14.3)	3 (1.9)
Blood groups
A	20 (13.0)	23 (14.9)	0.046
B	34 (22.1)	22 (14.3)
AB	6 (7.9)	3 (3.8)
O	16 (21.1)	30 (19.5)
Pathological types
Adenosquamous carcinoma	0 (0)	3 (1.9)	0.137
Adenocarcinoma	75 (48.7)	75 (48.7)
Papillocarcinoma	1 (0.6)	0 (0.0)
Degree of differentiation
Poor	36 (23.4)	24 (15.6)	0.047
Moderate-well	40 (26.0)	54 (35.1)
Resection margin status
Negative	39 (25.3)	57 (37.0)	0.008
Positive	37 (24.0)	21 (13.6)
Maximum tumor diameter (cm)
≤ 2.45	36 (23.4)	32 (20.8)	0.516
> 2.45	40 (26.0)	46 (29.9)
T stage
Tis-T1a	2 (1.3)	8 (5.2)	0.021
T1b-T2b	9 (5.8)	20 (13.0)
T3	58 (37.7)	45 (29.2)
T4	7 (4.5)	5 (3.2)
N stage
N0	45 (29.2)	53 (34.4)	0.403
N1	25 (16.2)	22 (14.3)
N2	6 (3.9)	3 (1.9)
Distant metastasis
Absent	67 (43.5)	75 (48.7)	0.077
Present	9 (5.8)	3 (1.9)
TNM stage
0-Istage	3 (1.9)	13 (8.4)	0.007
IIA-IIB stage	6 (3.9)	10 (6.5)
IIIA-IIIB stage	46 (29.9)	46 (29.9)
IVA-IVB stage	21 (13.6)	9 (5.8)
CA199 (U/mL)
≤ 39	24 (15.6)	42 (27.3)	0.006
> 39	52 (33.8)	36 (23.4)
Fibrinogen concentration (g/L)			0.111
≤ 3.47g/L	32 (20.8)	43 (27.9)
> 3.47 g/L	44 (28.6)	35 (22.7)
FAR
≤ 0.08	21 (13.6)	50 (32.5)	< 0.001
> 0.08	55 (35.7)	28 (18.2)

FAR: Fibrinogen to albumin ratio.