Role of colectomy in preventing recurrent primary sclerosing cholangitis in liver transplant recipients

Table 2 Demographics of study cohorts comparing liver transplantation recipients with and without recurrent primary sclerosing cholangitis in the liver graft

Ref.	Year	Study period	Number n(rPSC vs no rPSC)	Time to diagnosis of rPSC (yr)	Follow-up (yr)	Recipient age at LT (yr)	Recipient gender (male)	MELD at LT	Donor age (yr)	Donor gender (male)	Donor type (DBD)
Cholongitas et al[21]	2008	1989-2004	7 (13) vs 46 (87)	5 (0.3-10)1	9.1 (1-15.4)1	35 ± 15 vs 42 ± 132	5 (71) vs 25 (54)	NR	33 ± 18 vs 44 ± 142	6 (86) vs 27 (59)	NR
Alabraba et al[20]	2009	1986-2006	61 (23) vs 202 (77)	4.6 (0.5-12.9)1	6.9 (0-19.9)1	48 (16-72)1	50 (82) vs 149 (74)	NR	NR	NR	61 (100) vs 202 (100)
Moncrief et al[24]	2010	1989-2006	15 (25) vs 44 (75)	3.4 (1.5-5.5)	5.7 (2.8-8.8)	45 (36-53) vs 47 (37-52)	13 (87) vs 33 (75)	18 (13-21) vs 14 (10-21)	NR	NR	NR
Gelley et al[22]	2014	1995-2011	6 (24) vs 19 (76)	NR	NR	27 ± 7 vs 37 ± 122	3 (50) vs 13 (68)	16 ± 5 vs 11 ± 42	39 ± 14 vs 35 ± 112	NR	NR
Ravikumar et al[25]	2015	1990-2010	81 (14) vs 484 (86)	NR	9 (5-14)	43 (34-55) vs 49 (41-57)	61 (75) vs 344 (71)	NR	39 (28-53) vs 43 (32-54)	46 (57) vs 268 (55)	80 (99) vs 467 (96)
Hildebrand et al[23]	2016	1990-2006	62 (20) vs 243 (80)	4.6 (0.5-14.3)3	8.2 (0-22)3	39 ± 11.5 vs 39 ± 10.82	48 (77) vs 160 (66)	16 ± 6 vs 14 ± 72	43.6 ± 16 vs 40.1 ± 16.92	NR	NR

Data are reported as n (%) and median (interquartile range) unless indicated as

¹median (range),

²mean ± SD and

³mean (range). DBD: Donation after brain death; LT: Liver transplantation; MELD: Model of end-stage liver disease; NR: Not reported; rPSC: Recurrent primary sclerosing cholangitis.