Hepatitis C virus core protein-induced miR-93-5p up-regulation inhibits interferon signaling pathway by targeting IFNAR1

doi:10.3748/wjg.v24.i2.226

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2018; 24(2): 226-236
Published online Jan 14, 2018. doi: 10.3748/wjg.v24.i2.226

Table 3 Receiver operating characteristics curve analysis of serum miR-93-5p concentration

AUC	Sensitivity	Specificity	Cut-off value (amol/μL)
0.8846 (Infection vs Healthy)	0.7619	1	0.009774
0.8562 (Sensitivity vs Healthy)	0.7000	1	0.009774
0.9265 (Infection vs Resistance)	0.8529	1	0.010870
0.8359 (Resistance vs Sensitivity)	0.7647	1	0.030300

Infection: HCV-1b-infected patients; Healthy: Healthy subjects; Sensitivity: Patients with pegylated IFNα sensitivity; Resistance: Patients with pegylated IFNα resistance.

Citation: He CL, Liu M, Tan ZX, Hu YJ, Zhang QY, Kuang XM, Kong WL, Mao Q. Hepatitis C virus core protein-induced miR-93-5p up-regulation inhibits interferon signaling pathway by targeting IFNAR1. World J Gastroenterol 2018; 24(2): 226-236
URL: https://www.wjgnet.com/1007-9327/full/v24/i2/226.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i2.226