Microbiota modification by probiotic supplementation reduces colitis associated colon cancer in mice

Figure 5 Probiotic supplementation does not modify the tumour microenvironment. Real-time RT-PCR analysis of TNF-α (A), IL-6 (B), IL-1β (C), IL-10 (D), TGF-β1 (E), and IL-13 (F), IL-4(G) in colon tumour tissue of control and probiotic groups; results are presented relative to those of Gapdh. H: Concentration of cytokines in the tumour tissue analysed by Bio-Plex Multiplex cytokine assay at day 60 after injection with azoxymethane. Mann-Whitney U test. Data from two independent experiments, presented as mean and standard deviation.