Basic Study
Copyright ©The Author(s) 2018.
World J Gastroenterol. May 14, 2018; 24(18): 2009-2023
Published online May 14, 2018. doi: 10.3748/wjg.v24.i18.2009
Table 1 Comparison of modified Swerdlow et al[21,27,28] and Park/Chiu et al[22,26] systems for grading of histological damage on the intestine
GradeModified SwerdlowPark/Chiu
0No pathological changeNormal mucosa
1Focal loss of surface epitheliumSubepithelial space at villus tips
2Mucosal infarction (extensive loss of surface epithelium, loss of variable amounts of lamina propria, sparing of basal glands, intact muscularis mucosae)Extension of subepithelial space with moderate lifting
3Submucosal infarction (variable necrosis of submucosa, complete mucosal necrosis, intact muscularis mucosae)Massive lifting down the sides of the villi, some denuded tips
4Mural infarction (loss of muscularis mucosae, complete necrosis of mucosa and submucosa)Denuded villi, dilated capillaries
5Mural infarction (involvement of inner layer of muscularis propria, complete necrosis of mucosa and submucosa)Disintegration of lamina propria
6Transmural infarction (complete necrosis of the bowel wall)Crypt layer injury
7Transmucosal infarction
8Transmural infarction