Punctual mutations in 23S rRNA gene of clarithromycin-resistant Helicobacter pylori in Colombian populations

doi:10.3748/wjg.v24.i14.1531

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Apr 14, 2018; 24(14): 1531-1539
Published online Apr 14, 2018. doi: 10.3748/wjg.v24.i14.1531

Table 4 Punctual mutations in 23S rRNA gene of Helicobacter pylori from the population at high-risk of gastric cancer, according to susceptibility or resistance to clarithromycin

Resistant n = 4			Susceptible n = 6
Patient ID	Mutations	MIC	Patient ID	Mutations	MIC

323	A1593G/A1822G/G1827A/T1645C/T1831C/¹T2183C	1	351	A1822G/G1827A/T1831C	< 0.25
336	A1593G/¹C2196T	2	377	A1822G/G1827A/G2221A/T1645C/T1831C	< 0.25
339	¹A2144G/G1827A	4	394	A1593G	< 0.25
440	A1822G/G1827A/G2221A/T1831C	4	457	A1822G/G1827A/G2221A/T1831C	< 0.25
			467	A1739G/G1695A	< 0.25
			513	A1822G/G1827A/T1831C	< 0.25
ATCC 700392	A1593G		ATCC 43504	A1667G/T1668C

¹Unique mutations of Helicobacter pylori resistant to clarithromycin. MIC: Minimum inhibitory concentration (μg/mL).

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Citation: Matta AJ, Zambrano DC, Pazos AJ. Punctual mutations in 23S rRNA gene of clarithromycin-resistant Helicobacter pylori in Colombian populations. World J Gastroenterol 2018; 24(14): 1531-1539
URL: https://www.wjgnet.com/1007-9327/full/v24/i14/1531.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i14.1531

Matta AJ, Zambrano DC, Pazos AJ. Punctual mutations in 23S rRNA gene of clarithromycin-resistant Helicobacter pylori in Colombian populations. World J Gastroenterol 2018; 24(14): 1531-1539 [PMID: 29662291 DOI: 10.3748/wjg.v24.i14.1531]

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