Proteinase-activated receptor 2 promotes tumor cell proliferation and metastasis by inducing epithelial-mesenchymal transition and predicts poor prognosis in hepatocellular carcinoma

Figure 2 Proteinase-activated receptor 2 knockdown and overexpression. A: qRT-PCR analysis of the proteinase-activated receptor 2 (PAR2) mRNA expression levels in HepG2 and SMMC-7721 cells with PAR2 knockdown; B: Immunoblot analysis of the protein levels of PAR2 in HepG2 and SMMC-7721 cells with PAR2 knockdown; C: The RNA expression levels of PAR2 in HepG2 and SMMC-7721 cells with PAR2 overexpression were measured by qRT-PCR; D: The protein levels of PAR2 in HepG2 and SMMC-7721 cells with PAR2 overexpression were measured by immunoblot analysis. ^bP < 0.01.