Emodin and baicalein inhibit sodium taurocholate-induced vacuole formation in pancreatic acinar cells

Figure 1 Therapeutic effects of combined use of emodin and baicalein on severe acute pancreatitis rats. Animals received CEB or an equal amount of saline injection after the SAP induction. CEB at high, middle, and low doses was administered immediately after the SAP induction. Animals were sacrificed 12 h after the SAP induction and were assessed for (A) representative images of pancreatic histopathology in all groups (H&E, ×100). (a) Control group; (b) SO group; (c) SAP group; (d) CEB high-dose group; (e) CEB middle-dose group; (f) CEB low-dose group. B: Histopathology score evaluation; C: Serum amylase; D: Serum cytokines. The data represent the mean ± SD. ^aP < 0.05 vs the control group; ^cP < 0.05 vs the SAP group.