Correlation between smoking habit and surgical outcomes on viral-associated hepatocellular carcinomas

Table 3 Multivariate analyses for current smokers vs others (hepatitis C virus, n = 273)

Type	Characteristics	HR (95%CI)	P value
DFS	Smoking habit (current)	1.22892 (0.8736, 1.7287)	0.2364
	Age (67 < yr)	0.98815 (0.7442, 1.3121)	0.9343
	Gender (male)	0.9536 (0.6797, 1.338)	0.7833
	Alcohol abuse	0.55622 (0.3803, 0.8135)	0.0025
	BMI (median <)	0.70403 (0.5284, 0.9381)	0.0165
	ICG R15 (median <)	1.59531 (1.1763, 2.1635)	0.0027
	T factor (T3/4)	1.90638 (1.4279, 2.5452)	< 0.0001
OS	Smoking habit (current)	1.69259 (1.1844, 2.4187)	0.0039
	Age (67 < yr)	1.18434 (0.8668, 1.6182)	0.2880
	Gender (male)	1.01654 (0.687, 1.504)	0.9346
	Alcohol abuse	0.74612 (0.5061, 1.1)	0.1392
	BMI (median <)	0.89005 (0.6489, 1.2208)	0.4701
	ICG R15 (median <)	1.32015 (0.9524, 1.83)	0.0955
	T factor (T3/4)	1.74555 (1.2767, 2.3865)	0.0005
DSS	Smoking habit (current)	1.68394 (1.0201, 2.7798)	0.0416
	Age (67 < yr)	1.00555 (0.6464, 1.5644)	0.9804
	Gender (male)	1.25081 (0.6981, 2.2412)	0.4520
	Alcohol abuse	0.66203 (0.3796, 1.1547)	0.1462
	BMI (median <)	0.97081 (0.6206, 1.5185)	0.8967
	ICG R15 (median <)	1.18278 (0.7484, 1.8692)	0.4722
	T factor (T3/4)	1.67615 (1.0752, 2.613)	0.0226

DFS: Disease-free survival; OS: Overall survival; DSS: Disease-specific survival.