Do pathological variables have prognostic significance in rectal adenocarcinoma treated with neoadjuvant chemoradiotherapy and surgery?

Figure 1 Tumor regression in rectal surgical specimens after neo-adjuvant chemo-radiotherapy. A: Dworak grade 2, corresponding to dominant fibrosis with few neoplastic cells or groups; B: Dworak grade 4, showing no tumor cells (pathological complete response); C: Acellular mucin pools.