Anti-inflammatory intestinal activity of Combretum duarteanum Cambess. in trinitrobenzene sulfonic acid colitis model

Figure 5 Effect of acute administration of Cd-EtOHE at 125 mg/kg and Cd-HexP at 62. 5 mg/kg on myeloperoxidase activity (MPO, U/mg protein) (A), tumor necrosis factor-alpha (TNF-α, pg/mg protein) (B), interleukin-1β (IL-1β, pg/mg protein) (C), interleukin-10 (IL-10, pg/mg protein) (D) in trinitrobenzene sulfonic acid-induced colitis model with relapse in rats (TNBS, 10 mg/animal). Data are expressed as the mean ± SEM. ^aP < 0.05, ^bP < 0.01 and ^cP < 0.001 vs colitic group. ^dP < 0.05, ^eP < 0.01 and ^fP < 0.001 vs non-colitic group. Cd: Combretum duarteanum; HexP: Hexane phase; EtOHE: Ethanolic extract.