Do pathological variables have prognostic significance in rectal adenocarcinoma treated with neoadjuvant chemoradiotherapy and surgery?

Table 2 Statistical correlations between Dworak regression grade and clinico-pathological variables

Variable	Dworak regression grade					P value
	0	1	2	3	4
Sex
M	23	52	29	11	26	0.285
F	11	24	21	10	8
Age
≤ 67 yr	14	35	32	9	16
> 67 yr	20	41	18	12	18	0.202
Site
Upper	9	37	22	8	17
Medium	7	11	7	1	6
Lower	13	23	19	11	11
Extensive	5	5	2	1	0	0.2506
Circumferential spread
One-third	14	30	28	8	14
Middle	12	19	10	9	12
Complete	8	27	12	4	8	0.31
Craniocaudal extension
< 3 cm	8	15	13	6	9
≥ 3 cm	26	61	37	15	25	0.873
Distance from the anal verge
≥ 1 cm	2	4	2	2	1
< 1 cm	32	72	48	19	33	0.853
Histological grade
1	1	3	2	0	0
2	28	61	36	20	34
3	5	12	12	1	0	0.0732
Histotype
NOS	28	71	49	20	32
Mucinous	6	5	1	1	2	0.0875
cT
2	2	2	5		3
3	23	63	37	18	29
4	9	11	8	3	2	0.219
cN
cN0	14	28	21	10	25
cN+	20	48	29	11	9	0.008
Death due to disease
No	18	56	34	18	31
Yes	16	20	16	3	3	0.0047
Recurrence
No	15	50	34	17	26
Yes	19	26	16	4	8	0.0254