Impact of smoking habit on surgical outcomes in non-B non-C patients with curative resection for hepatocellular carcinoma

Table 4 Comparison of current smoking status and clinicopathological factors (n = 83)

	Current (n = 24)	Never + Ex (n = 59)	P value
Age, yr (mean ± SD)	59.4 ± 12.0	69.3 ± 10.2	0.0002
Gender (male/female)	22/2	44/15	0.0803
Alcohol abuse (+/-)	10/14	9/50	0.0188
Diabetes mellitus (+/-)	8/16	21/38	0.8448
Obesity (+/-)	6/18	20/39	0.6024
ICG R15 (%)	11.7 ± 1.8	14.8 ± 1.2	0.1235
Tumor size (mean ± SD mm)	68.4 ± 44.0	63.9 ± 40.6	0.6724
Solitary/Multiple	10/14	42/17	0.023
Vp (+/-)	9/15	23/36	0.8998
T factor (T12/T34)	10/24	33/26	0.3329
AFP (mean ± SD)	4450 ± 14563.6	3235 ± 13042	0.6442
Fibrosis (F12/F34, n = 82)	11/13	36/22	0.2224
Recurrence (+/-)	16/8	32/27	0.3362
Therapy for recurrent tumor (+/-)1	14/2	27/5	0.7724
TAE only	11	14
Surgical resection	1	5
Ablation	1	2
Chemotherapy	1	3
Multiple therapy2	0	3
Tumor-related death (%)	13 (54.2)	17 (28.8)	0.0293
Other cause of death (%)	5 (20.8)	11 (18.6)	0.8187

¹Comparison restricted in recurrent case;

²Two cases of TAE + operation and one case of TAE + ablation. ICG R15: Indocyanine green retention rate at 15 min; TAE: Transcatheter arteriography embolization; Vp: Portal vein invasion.