Molecular mechanisms of apoptosis in hepatocellular carcinoma cells induced by ethanol extracts of Solanum lyratum Thumb through the mitochondrial pathway

Table 5 Differences in mRNA expressions of genes relating to hepatocellular carcinoma SMMC-7721 cells in each group

Group	Concentration, C/mg•L-1	2-ΔΔCT
		Fas	FasL	Caspase-8	Caspase-3	p53	Bcl-2
Negative control group	0	1	1	1	1	1	1
Three ST groups with different concentrations	2.5	1.06 ± 0.06	2.30 ± 0.93a	1.08 ± 0.04	1.10 ± 0.12	1.13 ± 0.11	3.09 ± 0.59a
	5	1.34 ± 0.25a	9.02 ± 0.32b	1.47 ± 0.31a	1.50 ± 0.27a	1.43 ± 0.16a	9.46 ± 0.58b
	10	1.63 ± 0.14a	31.34 ± 0.13b	2.02 ± 0.71a	1.82 ± 0.40a	1.75 ± 0.25a	47.29 ± 0.68b
Positive control group	5	1.33 ± 0.17a	10.02 ± 0.57b	1.49 ± 0.30a	1.50 ± 0.19a	1.47 ± 0.11a	8.92 ± 0.09b

By comparing the ST group with the negative control group.

^aP < 0.05,

^bP < 0.01, vs control groups. ST: Solanum lyratum Thumb.