Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights

doi:10.3748/wjg.v23.i48.8465

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Dec 28, 2017 (publication date) through Sep 22, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 28, 2017; 23(48): 8465-8488
Published online Dec 28, 2017. doi: 10.3748/wjg.v23.i48.8465

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Figure 24 In IC + RL rats, 15 min of ligation followed by 15 min of full reperfusion period resulted in the appearance of even more mucosal and submucosal edema as well as more pronounced cyanosis (controls, upper, HE, 4 × objective). This was consistently attenuated by BPC 157 treatment after the initiation of reperfusion (lower, HE, 4 × objective).

Citation: Duzel A, Vlainic J, Antunovic M, Malekinusic D, Vrdoljak B, Samara M, Gojkovic S, Krezic I, Vidovic T, Bilic Z, Knezevic M, Sever M, Lojo N, Kokot A, Kolovrat M, Drmic D, Vukojevic J, Kralj T, Kasnik K, Siroglavic M, Seiwerth S, Sikiric P. Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights. World J Gastroenterol 2017; 23(48): 8465-8488
URL: https://www.wjgnet.com/1007-9327/full/v23/i48/8465.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i48.8465