Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights

Figure 2 Progressive disappearance (A, saline bath; B, C, left) or recovery (BPC 157 bath; B, C, right) of blood vessels after ligation of the dorsal colon of IC rats (USB microscope camera). Ligation course before therapy (A); ligation course after therapy (B, C). A. Left colic artery and vein major arcade vessels obstructed by two ligations, proximal (left) and distal (right) (L), arcade vessels outside 0, 4 (black circles) or inside 1, 2, 3 (white circles), inside-outside connection absent (arcade 3-arcade 4) (white arrows). B. Five minutes later: inside-outside connection still absent (saline bath, left) (white arrow) or reestablished (black arrow); vessel presentation markedly increased (BPC 157 bath, right). C. From the 10th minute through the end of the 15th minute. Progressive vessel disappearance (saline bath, left) (white arrow); recovered blood vessels (BPC 157 bath, right) (black arrow).