Prognostic value of lymph node metastasis in patients with T1-stage colorectal cancer from multiple centers in China

Table 4 COX regression analysis of correlation between clinicopathological parameters and 5-year overall survival

	RR	P value	95%CI
			Lower bound	Upper bound
Gender, Male vs Female	1.784	0.182	0.695	6.816
Age (yr), < 60 vs ≥ 60	3.805	0.051	0.995	9.034
Smoking, No vs Yes	0.590	0.442	0.413	7.565
Preoperative CEA, (ng/mL), < 5 vs ≥ 5	1.121	0.290	0.580	6.206
Preoperative CA199, (ng/mL), < 9 ≥ 9	6.452	0.011	1.411	14.481
Preoperative CA724, (ng/mL), < 2 ≥ 2	0.935	0.333	0.201	1.725
Granulocyte absolute value, < 2.2 vs ≥ 2.2	0.040	0.841	0.171	8.761
D-dimer, < 0.21 ≥ 0.21	2.373	0.123	0.777	8.217
Preoperative hemoglobin, < 132 vs ≥ 132	0.577	0.448	0.198	2.042
Tumor size (cm), < 3 vs ≥ 3	0.581	0.446	0.261	21.193
Vascular invasion, No vs Yes	0.343	0.558	0.468	4.076
Tumor location, Rectum vs Colon	0.210	0.647	0.310	2.068
Differentiation degree, High/moderate vs Low	1.031	0.310	0.435	13.792
Tumor general type, Ulcer vs Non-ulcer	2.338	0.126	0.811	5.471
Tumor tissue type, Non-adenocarcinoma vs Adenocarcinoma	0.783	0.376	0.068	2.755
Lymph node metastasis, No vs Yes	5.328	0.021	1.264	17.592