Prognostic value of lymph node metastasis in patients with T1-stage colorectal cancer from multiple centers in China

Table 1 Univariate analysis of correlation between lymph node metastasis and clinicopathological parameters of T1-stage colorectal cancer patients

Clinicopathological characteristic	n	Lymph node metastasis		χ2	P value
		Yes	No
Gender				1.955	0.162
Male	172	11	161
Female	149	16	133
Age (yr)				0.436	0.509
≥ 60	174	13	161
< 60	147	14	133
Smoking				0.766	0.382
No	279	22	257
Yes	42	5	37
Preoperative CEA (ng/mL)				5.994	0.014
< 5	284	20	264
≥ 5	37	7	30
Preoperative CA199 (ng/mL)				5.015	0.025
< 9	173	9	164
≥ 9	148	18	130
Preoperative CA724 (ng/mL)				12.275	0.000
< 2	163	5	158
≥ 2	158	22	136
Granulocyte absolute value				0.771	0.380
< 2.2	32	4	28
≥ 2.2	289	23	266
D-dimer				2.227	0.136
< 0.21	158	17	141
≥ 0.21	163	10	153
Preoperative hemoglobin				1.504	0.220
< 132	154	16	138
≥ 132	167	11	156
Vascular invasion				18.421	0.000
No	313	23	290
Yes	8	4	4
Tumor location				1.184	0.277
Rectum	170	17	153
Colon	151	10	141
Tumor size (cm)				1.526	0.217
< 3	190	19	171
≥ 3	131	8	123
Differentiation degree				7.723	0.005
High/moderate	307	23	284
Low	14	4	10
Tumor general type				0.219	0.640
Ulcer	238	19	219
Non-ulcer	83	8	75
Tumor tissue type				2.293	0.130
Non-adenocarcinoma	9	2	7
Adenocarcinoma	312	25	287