Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights

Table 2 Assessment of colon lesions in rats subjected to two ligations of the left colic artery and vein for 15 min followed by reperfusion for next 15 min (IC+RL rats) (pale flat areas without mucosal folds were measured and are shown as a percentage of the area of the blood-deprived and the reperfused colon segment; mean ± SD)

Medication (/kg, 1 ml bath/rat) applied to the 25-mm blood-flow-deprived and then reperfused colon segment	Pale areas without mucosal folds as a percentage of the area of the blood-flow-deprived and then reperfused colon segment (mean ± SD)
0.9% NaCl (control)	86 ± 8
BPC 157 (10 µg)	10 ± 2a

At 1 min reperfusion time, BPC 157 (10 µg/kg, 1 mL bath/rat) or an equal volume of saline bath (control) was applied to the 25-mm blood-flow-deprived colon segment.

^aP < 0.05 at least vs control.