Pharmacokinetics and pharmacodynamics of Shengjiang decoction in rats with acute pancreatitis for protecting against multiple organ injury

doi:10.3748/wjg.v23.i46.8169

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 14, 2017; 23(46): 8169-8181
Published online Dec 14, 2017. doi: 10.3748/wjg.v23.i46.8169

Table 2 Component concentrations of Shengjiang decoction in the pancreas (ng/mL) (n = 6)

Group	Emodin	ALEM	Rhein	CHRY	Curcumin	DEME	BISD
CG + SJD	0.79 ± 0.38	0.29 ± 0.15	96.52 ± 31.35	0.54 ± 0.37	4.64 ± 2.74	0.22 ± 0.12	0.14 ± 0.03
MG + SJD	1.08 ± 0.30	0.26 ± 0.10	31.41 ± 13.27^a	0.58 ± 0.22	6.08 ± 2.77	0.20 ± 0.05	0.59 ± 0.22^a

^aP < 0.05 vs CG + SJD. ALEM: Aloe-emodin; CHRY: Chrysophanol; DEME: Demethoxycurcumin; BISD: Bisdemethoxycurcumin.

Citation: Zhu L, Li JY, Zhang YM, Kang HX, Chen H, Su H, Li J, Tang WF. Pharmacokinetics and pharmacodynamics of Shengjiang decoction in rats with acute pancreatitis for protecting against multiple organ injury. World J Gastroenterol 2017; 23(46): 8169-8181
URL: https://www.wjgnet.com/1007-9327/full/v23/i46/8169.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i46.8169