Retreatment of patients with treatment failure of direct-acting antivirals: Focus on hepatitis C virus genotype 1b

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 14, 2017; 23(46): 8120-8127
Published online Dec 14, 2017. doi: 10.3748/wjg.v23.i46.8120

Table 1 Representative direct-acting antivirals, their targets and hepatitis C virus genotypes

Target regions	DAAs	HCV GTs
NS3/4A	Glecaprevir	Pan-GTs
	Grazoprevir	1, 4
	Asunaprevir	1b
	Paritaprevir	1, 2a, 4
	Simeprevir	1, 4
	Telaprevir	1, 2
	Boceprevir	1
NS5A	Pibrentasvir	Pan-GTs
	Velpatasvir	Pan-GTs
	Elbasvir	Pan-GTs
	Daclatasvir	Pan-GTs
	Ledipasvir	1, 4, 5
	Ombitasvir	1, 4
NS5B	Sofosbuvir [nucleos(t)ide inhibitor]	Pan-GTs
	Dasabuvir [non-nucleos(t)ide inhibitor]	1

DAAs: Direct-acting antivirals; HCV GTs: Hepatitis C virus genotypes.

Citation: Kanda T, Nirei K, Matsumoto N, Higuchi T, Nakamura H, Yamagami H, Matsuoka S, Moriyama M. Retreatment of patients with treatment failure of direct-acting antivirals: Focus on hepatitis C virus genotype 1b. World J Gastroenterol 2017; 23(46): 8120-8127
URL: https://www.wjgnet.com/1007-9327/full/v23/i46/8120.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i46.8120

Kanda T, Nirei K, Matsumoto N, Higuchi T, Nakamura H, Yamagami H, Matsuoka S, Moriyama M. Retreatment of patients with treatment failure of direct-acting antivirals: Focus on hepatitis C virus genotype 1b. World J Gastroenterol 2017; 23(46): 8120-8127 [PMID: 29290649 DOI: 10.3748/wjg.v23.i46.8120]

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