Down-regulation of miR-30a-3p/5p promotes esophageal squamous cell carcinoma cell proliferation by activating the Wnt signaling pathway

Figure 1 Expression of miR-30a-3p and miR-30a-5p in esophageal squamous cell carcinoma tissues and matched adjacent normal tissues. A and B: Analyses of miR-30a-3p and miR-30a-5p expression in ESCC tissues (n = 119) and matched adjacent normal tissues (n = 119). Accession number of the public microarray data from GEO database is GSE43732; C: Validation through qPCR of miR-30a-3p and miR-30a-5p expression patterns in 99 cases of fresh ESCC biopsies and their paired adjacent normal tissues. The expression levels of mRNA were normalized with U6. Fold changes of miR-30a-3p/5p were calculated by the ratio of miR-30a-3p/5p expression in ESCC tissues (T) and matched to adjacent normal tissues (N); ^aP < 0.05.