©The Author(s) 2017.
World J Gastroenterol. Dec 7, 2017; 23(45): 8017-8026
Published online Dec 7, 2017. doi: 10.3748/wjg.v23.i45.8017
Published online Dec 7, 2017. doi: 10.3748/wjg.v23.i45.8017
Table 3 Characteristics of pediatric patients receiving liver transplantation with maternal graft (n = 17) according to the presence or absence of pretransplantation HLA-DR NIMA-MC and HLA-DR match status n (%)
| Factors1 | NIMA-MC (+) or HLA-DR identity with mother | NIMA-MC (-) | P value |
| (n = 7) | (n = 10) | ||
| Age at the time of transplantation in years, median (range) | 5.6 (0.8-10) | 7.3 (0.8-16) | 0.42 |
| Age at the time of transplantation (less than 12 mo) | 3 (42.9) | 4 (40.0) | > 0.99 |
| Sex, male: female | 3 (42.9): 4 (57.1) | 4 (40.0): 6 (60.0) | > 0.99 |
| Recipient weight, kg, median (range) | 27.4 (6.2-54.5) | 26.0 (9.6-56.3) | > 0.99 |
| Original liver disease | 0.64 | ||
| Biliary atresia | 4 (57.1) | 4 (40.0) | |
| Others | 3 (42.9) | 6 (60.0) | |
| Crossmatch positivity | 0 (0) | 1 (10.0) | > 0.99 |
| ABO identical to that of mother | 7 (100) | 7 (70.0) | 0.23 |
| PELD score, median (range) | 11.2 (-7.7-39) | 2.3 (-10.0-14.1) | 0.27 |
| The year of LT (before 2007) | 2 (28.6) | 3 (30.0) | > 0.99 |
| Donor age in years, median (range) | 34 (26-39) | 38 (33-43) | 0.16 |
| Sex match, yes: no | 4:3 | 6:4 | 0.65 |
| Operation time, median, min, median (range) | 443 (300-595) | 492 (285-710) | 0.46 |
| Graft vs recipient weight ratio, %, median (range) | 2.68 (1.62-3.23) | 2.15 (1.23-2.96) | 0.40 |
| Follow-up duration, mo, median (range) | 84 (63-176) | 66 (30-114) | 0.32 |
| Graft failure | 0 (0) | 0 (0) | > 0.99 |
| Biopsy-proven cellular rejection | 0 (0) | 5 (50) | 0.04 |
- Citation: Yi NJ, Park MS, Song EY, Ahn HY, Byun J, Kim H, Hong SK, Yoon K, Kim HS, Ahn SW, Lee HW, Choi Y, Lee KW, Suh KS, Park MH. Pretransplantation fetal-maternal microchimerism in pediatric liver transplantation from mother. World J Gastroenterol 2017; 23(45): 8017-8026
- URL: https://www.wjgnet.com/1007-9327/full/v23/i45/8017.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i45.8017