Metabolically based liver damage pathophysiology in patients with urea cycle disorders - A new hypothesis

doi:10.3748/wjg.v23.i44.7930

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Nov 28, 2017 (publication date) through Apr 29, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 28, 2017; 23(44): 7930-7938
Published online Nov 28, 2017. doi: 10.3748/wjg.v23.i44.7930

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Figure 3 Metabolic exchangeable pool of fumaric acid and succinic acid. In urea cycle disorders (UCDs) there is decreased or completely absent FA supply from the cytosol. FA deficient supply is proportional to the enzyme activity deficiency.

Citation: Ivanovski I, Ješić M, Ivanovski A, Garavelli L, Ivanovski P. Metabolically based liver damage pathophysiology in patients with urea cycle disorders - A new hypothesis. World J Gastroenterol 2017; 23(44): 7930-7938
URL: https://www.wjgnet.com/1007-9327/full/v23/i44/7930.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i44.7930