Chitinase 3-like 1 secreted by peritumoral macrophages in esophageal squamous cell carcinoma is a favorable prognostic factor for survival

Table 1 Levels of chitinase 3-like 1 and clinical and laboratory characteristics of 150 esophageal squamous cell carcinoma patients

Characteristics	No. of patients	Levels of CHI3L1
		Low	High	P value
All	150	97	53
Age				0.009
Median	60
Range	30-96
< 60	81	60	21
≥ 60	69	37	32
Sex				0.713
Male	113	74	39
Female	37	23	14
Smoking status				0.514
Smoker	99	66	33
Non-smoker	49	30	19
Alcohol intake				0.984
Yes	56	36	20
No	90	58	32
Grade				0.736
Grade 1	24	16	8
Grade 2	57	36	21
Grade 3	41	29	12
T status				0.886
pT 1/2	31	21	10
pT 3/4	113	75	38
N status				0.154
pN 0	63	46	17
pN 1/2/3	81	50	31
M status				0.156
pM 0	112	78	34
pM 1	32	18	14
Stage				0.712
I–II	51	35	16
III-IV	93	61	32
SCCA				0.539
≤ 1.5	101	67	34
> 1.5	49	30	19
CEA				0.389
≤ 5.0	132	87	45
> 5.0	18	10	8
Treatment				0.138
Surgery	73	49	24
Chemoradiotherapy	57	37	20
Chemotherapy	11	4	7

CHI3L1: Chitinase 3-like 1; SCCA: Squamous cell carcinoma antigen; CEA: Carcinoembryonic antigen.