Retrospective Study
Copyright ©The Author(s) 2017.
World J Gastroenterol. Oct 14, 2017; 23(38): 7025-7036
Published online Oct 14, 2017. doi: 10.3748/wjg.v23.i38.7025
Table 3 Postoperative data
VariableTotal,n = 1000First 10 yr,1993-2002Second 10 yr,2003-2012Last 5 yr,2013-2017P-value
Hospital stay in d8 (5-71)9880.0001
Time to oral intake in d5 (4-56)6550.33
Total amount of drainage in mL700 (40-35000)12006006000.0001
Drain removal in d8 (4-71)8880.03
Total postoperative complications323 (32.3)120 (40)131 (29.6)72 (27.9)0.02
Dindo grade
I114 (11.4)244743
II97 (9.7)4045120.11
III69 (6.9)36249
IV and V43 (4.3)20158
Severe complications, ≥ III
Minor211 (21.1)8492550.23
Major109 (10.9)566917
Pancreatic fistula139 (13.9)45 (15)56 (12.7)38 (14.7)0.01
Grade A67 (6.7)1433200.04
Grade B48 (4.8)201711
Grade C24 (2.4)1167
DGE180 (18)76 (25.3)67 (15.2)37 (14.3)0.06
Types of DGE
Secondary DGE152 (15.2)70 (23.3)54 (12.2)27 (10.5)0.03
Primary DGE28 (2.8)5 (1.7)13 (2.9)10 (3.9)
Pulmonary complications46 (4.6)20 (6.7)21 (4.8)5 (1.6)0.01
Bile leak73 (7.3)39 (13)19 (4.3)15 (5.8)0.001
Postoperative bleeding25 (2.5)13 (4.3)7 (1.6)5 (1.9)0.49
Pancreatitis20 (2)12 (4.3)7 (1.6)1 (0.4)0.004
Bleeding PG15 (1.5)8 (2.7)5 (1.2)2 (0.8)0.14
Wound infection50 (5)13 (4.6)25 (5.7)12 (4.7)0.77
Re-operation74 (7.4)25 (8.3)33 (7.5)16 (6.2)0.21
Recurrence321 (36.9)130 (50.4)125 (32.6)66 (28.7)0.0001
Hospital mortality43 (4.3)20 (6.6%)15 (3.4)8 (3.1)0.02
Postoperative chemoradiotherapy275 (27.5)0132 (29.9)143 (55.4)0.0001
Overall median survival in mo26 (1-300)2130370.0001
1 yr90%87%93%87%
3 yr33%19%37%64%
5 yr19%11%21%

  • Citation: El Nakeeb A, Askar W, Atef E, Hanafy EE, Sultan AM, Salah T, shehta A, Sorogy ME, Hamdy E, Hemly ME, El-Geidi AA, Kandil T, Shobari ME, Allah TA, Fouad A, Zeid MA, Eneen AAE, El-Hak NG, Ebidy GE, Fathy O, Sultan A, Wahab MA. Trends and outcomes of pancreaticoduodenectomy for periampullary tumors: A 25-year single-center study of 1000 consecutive cases. World J Gastroenterol 2017; 23(38): 7025-7036
  • URL: https://www.wjgnet.com/1007-9327/full/v23/i38/7025.htm
  • DOI: https://dx.doi.org/10.3748/wjg.v23.i38.7025