Risk factors for postoperative recurrence after primary bowel resection in patients with Crohn’s disease

Table 1 Demographic and clinical characteristics of the patients undergoing intestinal resection n (%)

Variables	Number of patients
	(n = 260)
SEX
Male	187 (71.9)
Female	73 (28.1)
Follow-up period, month	101 (12-193)
Age at diagnosis	23 (12-74)
Age at 1st operation	28 (15-74)
Age at 2nd operation	34 (22-59)
Montreal classification
Age at diagnosis, yr
A1 ( ≤ 16)	25 (9.6)
A2 (17-40)	215 (82.7)
A3 ( > 40)	20 (7.7)
Location
L1 (Terminal ileum)	113 (43.5)
L2 (Colon)	38 (14.6)
L3 (Ileocolon)	107 (41.2)
L4 (Isolated upper disease)	2 (0.8)
Behavior
B1 (Inflammatory)	6 (2.3)
B2 (Stricturing)	80 (30.8)
B3 (Penetrating)	174 (66.9)
Family history (Crohn's disease)	7 (2.7)
Presence of extraintestinal manifestation	20 (7.7)
Perianal disease
at diagnosis	122 (46.9)
after 1st operation	62 (23.8)
History of smoking	70 (26.9)
Current smoker	12 (4.6)
Ex-smoker	58 (22.3)
Non-smoker	190 (73.1)
Preoperative use of medication
Anti-TNF	27 (10.4)
5-ASA	223 (85.8)
Steroid	147 (56.5)
Immunomodulator1	128 (49.2)
Antibiotics2	128 (49.2)
Malignancy	163 (62.7)
Colorectal cancer	3 (1.2)
Lung cancer	1 (0.4)

¹Use of azathioprine/6-mercaptopurine or methotrexate;

²Ciprofloxacin or metronidazole. EIM: Extraintestinal manifestation; 5-ASA: Aminosalicylates; TNF: Tumor necrosis factor.