Basic Study
Copyright ©The Author(s) 2017.
World J Gastroenterol. Oct 7, 2017; 23(37): 6817-6832
Published online Oct 7, 2017. doi: 10.3748/wjg.v23.i37.6817
Table 2 Glycosylation-related differentially expressed genes associated with Helicobacter pylori infection of E12 cells
Gene symbolFold changeP valueGene name
Top 20 upregulated
LGALS7/7B2.310.0115Lectin, galactoside-binding, soluble, 7 /7B
UGGT11.980.0059UDP-glucose glycoprotein glucosyltransferase 1
ST3GAL51.900.0035ST3 beta-galactoside alpha-2,3-sialyltransferase 5
PARM11.870.0026Prostate androgen-regulated mucin-like protein 1
NAGK1.790.0016N-acetylglucosamine kinase
VSIG11.710.0240V-set and immunoglobulin domain containing 1
EDEM21.690.0032ER degradation enhancer, mannosidase alpha-like 2
MPDU11.690.0029Mannose-P-dolichol utilization defect 1
DPM21.610.0015Dolichyl-phosphate mannosyltransferase polypeptide 2, reg. s/u
LMAN21.600.0021Lectin, mannose-binding 2
GMPPB1.590.0019GDP-mannose pyrophosphorylase B
ALG31.590.0214Asn-linked glycosylation 3, alpha-1,3- mannosyltransferase hom.
GALK21.570.0027Galactokinase 2
DDOST1.530.0094Dolichyl-diphosphooligosaccharide--protein glycosyltransferase
MCAM1.530.0111Melanoma cell adhesion molecule
B3GALT61.530.0097UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
SLC35B11.510.0025Solute carrier family 35, member B1
ST6GALNAC41.500.0024ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
GMPPA1.490.0031GDP-mannose pyrophosphorylase A
ALDOC1.480.0020Aldolase C, fructose-bisphosphate
Top 20 downregulated
REG42.460.0018Regenerating islet-derived family, member 4
OGT2.250.0037O-linked N-acetylglucosamine (GlcNAc) transferase (OGT)
AMIGO22.220.0039Adhesion molecule with Ig-like domain 2
GALNT122.090.0033UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12
EXT11.990.0256Exostosin 1
LY751.860.0075Lymphocyte antigen 75 (CLEC13B)
PIGZ1.820.0072Phosphatidylinositol glycan anchor biosynthesis, class Z
UGP21.790.0320UDP-glucose pyrophosphorylase 2
MANEA1.790.0225Mannosidase, endo-alpha
ALG131.780.0138Asparagine-linked glycosylation 13 homolog (S. cerevisiae)
GBAP11.750.0035Glucosidase, beta, acid pseudogene 1
SLC35A31.730.0071Solute carrier family 35 (UDP-N-acetylglucosamine transporter), member A3
ST3GAL41.710.0032ST3 beta-galactoside alpha-2,3-sialyltransferase 4
B4GALNT31.710.0129Beta-1,4-N-acetyl-galactosaminyl transferase 3
HMMR1.700.0039Hyaluronan-mediated motility receptor (RHAMM)
B4GALT61.690.0134UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
MAN2A11.600.0034Mannosidase, alpha, class 2A, member 1
LGALS21.580.0127Lectin, galactoside-binding, soluble, 2
MAN1A11.530.0021Mannosidase, alpha, class 1A, member 1
MUC131.530.0038Mucin 13, cell surface associated
CD1641.520.0015CD164 molecule, sialomucin
B4GALT51.510.0071UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5