Glycosylation-related gene expression in HT29-MTX-E12 cells upon infection by Helicobacter pylori

Table 1 Differentially expressed genes associated with Helicobacter pylori infection of E12 cells

Gene symbol	P-value	Fold change	Gene name
Top 15 upregulated
1CLIP1	0.0025	5.42	CAP-GLY domain containing linker protein 1
C10orf118	0.0031	5.21	chromosome 10 open reading frame 118
TOP1	0.0352	5.09	topoisomerase (DNA) I
LARS	0.0054	5.02	leucyl-tRNA synthetase
CDC27	0.0073	4.95	cell division cycle 27 homolog (S. cerevisiae)
STIP1	0.0042	3.92	stress-induced-phosphoprotein 1
MALAT1	0.0077	3.82	metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
IL32	0.0021	3.54	interleukin 32
SLC39A6	0.0204	3.33	solute carrier family 39 (zinc), member 6
AHNAK2	0.0070	3.25	AHNAK nucleoprotein 2
HSP90AB1	0.0014	3.24	heat shock protein 90 kDa alpha (cytosolic), B1
ACTR2	0.0035	3.20	ARP2 actin-related protein 2 homolog (yeast)
EIF4G1	0.0349	3.16	eukaryotic translation initiation factor 4 gamma, 1
ACBD3	0.0253	3.14	acyl-CoA binding domain containing 3
CCND1	0.0222	3.09	cyclin D1
Top 15 downregulated
PDK4	0.0011	3.25	pyruvate dehydrogenase kinase, isozyme 4
BCAT1	0.0042	3.24	branched chain amino-acid transaminase 1, cytosolic
PELI1	0.0059	3.24	Pellino homolog 1 (Drosophila)
CYP3A5	0.0015	3.12	cytochrome P450, family 3, subfamily A, polypeptide 5
HPGD	0.0032	3.10	hydroxyprostaglandin dehydrogenase 15-(NAD)
LRRC31	0.0030	3.05	leucine rich repeat containing 31
KIAA1984	0.0082	2.97	KIAA1984
HNRNPD	0.0054	2.86	Heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
IL28A	0.0026	2.85	interleukin 28A (interferon, lambda 2)
DDX60	0.0026	2.84	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
PHF14	0.0021	2.82	PHD finger protein 14
LOC100288092	0.0025	2.82	Hypothetical protein LOC100288092
ZNF207	0.0027	2.82	zinc finger protein 207
NCOA2	0.0025	2.81	nuclear receptor coactivator 2
AHSA2	0.0064	2.72	AHA1, activator of heat shock 90 kDa protein ATPase homolog 2 (yeast)

¹qRT-PCR analysis showed CLIP1 was downregulated.