Effect of local wound infiltration with ropivacaine on postoperative pain relief and stress response reduction after open hepatectomy

Table 2 Visual analog scale scores at rest and on movement, mean arterial pressure, heart rate, and cumulative sufentanil consumption

Characteristic	0 h	6 h	12 h	24 h	48 h1
VAS at rest
Ropivacaine group	2.38 ± 0.50	2.27 ± 0.45	2.04 ± 0.20	2.12 ± 0.33	2.08 ± 0.27
Control group	2.78 ± 0.58	2.67 ± 0.48	2.48 ± 0.51	2.22 ± 0.42	2.15 ± 0.36
t	-2.65	-3.17	-4.21	-1.03	-0.81
P value	0.0106	0.0032	0.0002	0.3096	0.4230
VAS on movement
Ropivacaine group	3.27 ± 0.53	3.35 ± 0.63	3.31 ± 0.62	3.23 ± 0.43	3.11 ± 0.52
Control group	3.63 ± 0.56	3.85 ± 0.60	3.78 ± 0.64	3.41 ± 0.57	3.30 ± 0.47
t	-2.39	-2.99	-2.72	-1.27	-1.34
P value	0.0208	0.0043	0.0089	0.2110	0.1857
MAP (mmHg)
Ropivacaine group	95.88 ± 5.08	93.35 ± 4.63	92.62 ± 4.43	94.73 ± 4.16	93.19 ± 3.41
Control group	97.74 ± 4.17	96.15 ± 4.14	97.56 ± 4.23	98.37 ± 3.99	94.89 ± 3.90
t	-1.46	-2.32	-4.16	-3.25	-1.69
P value	0.1515	0.0241	0.0001	0.0020	0.0981
HR (bpm)
Ropivacaine group	88.96 ± 4.12	90.19 ± 3.92	89.73 ± 4.45	91.65 ± 4.30	90.31 ± 4.45
Control group	92.04 ± 4.27	93.41 ± 4.62	94.74 ± 3.88	94.56 ± 3.43	92.11 ± 4.05
t	-2.66	-2.73	-4.37	-2.72	-1.54
P value	0.0103	0.0087	< 0.0001	0.0089	0.1289
Cumulative sufentanil consumption (μg)
Ropivacaine group	0	14.94 ± 2.56	30.40 ± 5.39	56.75 ± 6.20	83.02 ± 7.05
Control group	0	17.06 ± 3.81	35.50 ± 6.91	65.31 ± 7.09	91.39 ± 7.34
t		-2.36	-2.99	-4.67	-4.23
P value		0.0220	0.0043	< 0.0001	< 0.0001

¹As to cumulative sufentanil consumption, the time point was set at 36 h. VAS: Visual analog scale; MAP: Mean arterial pressure; HR: Heart rate.