Patients with inflammatory bowel disease have increased risk of autoimmune and inflammatory diseases

Table 4 Odds-ratios for immune mediated diseases restricted to either gender

Disease	Females	95%CI	Males	95%CI
IBD
Episcleritis	3.6a	2.1-6.1	2.9b	1.4-6.1
Atrophic gastritis	3.5a	2.1-5.9	-c
Polyarteritis nodosa	2.6a	1.5-4.5	-c
Rheumatoid arthritis	1.9a	1.6-2.2	1.4b	1.1-1.9
Giant cell arteritis	1.7a	1.3-2.2	-c
Psoriatic arthritis	1.6a	1.3-2.0	1.4b	1.1-1.9
Polymyalgia rheumatica	1.5a	1.3-1.8	-c
Sarcoidosis	1.5b	1.1-2.2	1.9a	1.3-2.6
UC
Atrophic gastritis	3.1a	1.7-5.8	-c
Rheumatoid arthritis	1.7a	1.4-2.1
Giant cell arteritis	1.7a	1.3-2.3	-c
Polymyalgia rheumatica	1.6a	1.3-2.0	-c
CD
Episclerit	5.9a	2.4-15.0	4.5b	1.2-17.5
Rheumatoid arthritis	2.3a	1.7-3.0	-c
Psoriatic arthritis	2.0a	1.3-2.8	-c
Sarcoidosis	-c		3.2a	1.6-6.6
Both1
Iridocyklitis	3.6a	1.9-6.8	2.7	1.2-6.2
Celiac disease	6.0a	1.9-18.6	3/0b2
Autoimmune hepatitis	17.9a	2.3-141.5	7.8b	0.9-69.8

^aP < 0.00125;

^bP = 0.0125-0.05;

^cP > 0.05;

¹Patients registered with both CD and UC;

²No. of cases in IBD cohort/No. of cases in control cohort. CD: Crohn’s disease; UC: Ulcerative colitis; IBD: Inflammatory bowel disease.