Effects and mechanism of adenovirus-mediated phosphatase and tension homologue deleted on chromosome ten gene on collagen deposition in rat liver fibrosis

Figure 2 Phosphatase and tension homologue deleted on chromosome ten has a negative effect on collagen deposition in vitro. A: Representative western blots of factors involved in the metabolism of fibrosis at 72 h posttransfection are shown in (A) and quantitated for rat primary HSCs in (B) and for human HSC LX2 cells in (C). Data in (B) and (C) are represented as mean ± SE. n = 3 for all groups. ^bP < 0.01 vs the control group; ^cP < 0.05 vs Ad-PTEN group; ^dP < 0.01 vs the Ad-GFP group. HSC: Hepatic stellate cell; PTEN: Phosphatase and tension homologue deleted on chromosome ten.