Systematic review and meta-analysis of colon cleansing preparations in patients with inflammatory bowel disease

Table 1 Recapitulative table with all included studies

Ref.	Arm1	Arm 2	Overall IBD type	Time of endoscopy
	Time to FD and LD to endoscopy	Time to FD and LD to endoscopy
Gould et al[23] 1982 (United Kingdom)	Castor oil 30 min (n = 23)	Senna 75 mg (n = 23)	RCH = 46	-
outpatient elective	LD: 24 h before	LD: 24 h before	CD = 0
Score: 3			Active disease = 7
Lazzaroni et al[12] 1993 (Italy)	PEG 4 L + placebo (n = 56)	PEG 4 L + simethicone 120 mg (n = 59)	RCH = 61	-
outpatient elective	FD: 2 L afternoon before	FD: 2L afternoon before	CD = 44
Score: 4	LD: 2 L 6 am day of	LD: 2L 6 am day of	Active disease = 0
Manes et al[13] 2015 (Italy)	PEG 4 L (n = 108)	PEG 2 L + bisacodyl 10 mg (n = 108)	RCH = 216	Between 8 am and 2 pm
outpatient elective	Whole dose (n = 48)	Whole dose (n = 35)	CD = 0
Score: 5	FD: 4 pm day before	FD: 4 pm day before	Active disease = 116
	Split dose (n = 60)	Split dose (n = 73)
	FD: 2 L day before	FD: 2 L day before
	LD: 2 L between 5 am and 7 am day of	LD: 2 L between 5 am and 7 am day of
Kim et al[24] 2017 (Korea)	PEG 4 L (n = 55)	PEG 2 L + ascorbate (n = 57)	RCH = 112	Between 9 am and 5 pm
outpatient elective	FD: 2 L 8 pm day before; LD: 2 L morning day of	FD: 2 L 8 pm day before, LD: 2 L morning day of	CD = 0
Score: 5	If colonoscopy scheduled in the afternoon, 4 L between 6 am and 8 am	If colonoscopy scheduled in the afternoon, 4 L between 6 am and 8 am	Active disease = 0

FD: First dose; LD: Last dose; IBD: Inflammatory bowel disease; PEG: Polyethylene glycol; CD: Crohn’s disease.