Threonine and tyrosine kinase may serve as a prognostic biomarker for gallbladder cancer

Table 1 Clinicopathological characteristics of the cohort

Characteristic	n (%)
Age (yr)
≤ 65	33 (48.5)
> 65	35 (51.5)
Gender
Female	39 (57.4)
Male	29 (42.6)
Cholecystolithiasis
Yes	41 (60.3)
No	27 (39.7)
Diabetes
Yes	17 (25.0)
No	51 (75.0)
Fever
Yes	9 (13.2)
No	59 (86.8)
Jaundice
Yes	15 (22.1)
No	53 (77.9)
ALT
Normal	53 (77.9)
Elevated	15 (22.1)
AST
Normal	50 (75.8)
Elevated	16 (24.2)
TBil
Normal	49 (72.1)
Elevated	19 (27.9)
DBil
Normal	50 (73.5)
Elevated	18 (26.5)
GGT
Normal	43 (69.4)
Elevated	19 (30.6)
ALP
Normal	45 (72.6)
Elevated	17 (27.4)
CEA
Normal	42 (72.4)
Elevated	16 (27.6)
CA 19-9
Normal	26 (44.1)
Elevated	33 (55.9)
Surgical type
Curative	35 (51.5)
Noncurative	33 (48.5)
Tumor size (cm)
≤ 3	43 (63.2)
> 3	25 (36.8)
Differentiation
Lowly-undifferentiated	15 (22.1)
Moderately-well	53 (77.9)
T stage
Tis	1 (1.5)
T1	3 (4.4)
T2	29 (42.6)
T3	35 (51.5)
N stage
N0	38 (55.9)
N1	22 (32.4)
N2	8 (11.7)
M stage
M0	60 (88.2%)
M1	8 (11.8%)
TNM stage
I	4 (5.9)
II	24 (35.3)
IIIA	9 (13.2)
IIIB	17 (25.0)
IVA	0 (0)
IVB	14 (20.6)

ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; TBil: Total bilirubin; DBil: Direct bilirubin; GGT: Gamma-glutamyl transpeptidase; ALP: Alkaline phosphatase; CEA: Carcinoembryonic antigen; CA 19-9: Carbohydrate antigen 19-9.