Yangzheng Sanjie decoction regulates proliferation and apoptosis of gastric cancer cells by enhancing let-7a expression

Figure 5 Effects of Yangzheng Sanjie decoction on let-7a and c-Myc expression in gastric cancer cells. A: Down-regulation of let-7a expression in GC cells; B and C: AGS and HS-746T GC cells were treated with 10% YCS or 10% normal rat serum for 48 h, and quantitative RT-PCR was performed to determine the expression levels of let-7a (B), while c-Myc expression was measured by Wester blot (C); D: Statistical analysis of Western blot data. ^aP < 0.05 vs the control group; ^bP < 0.01 vs the control group. YCS: YZSJD-containing serum; YZSJD: Yangzheng Sanjie decoction.