Prognostic factors associated with mortality in patients with gastric fundal variceal bleeding

Table 4 Baseline characteristics of patients with gastric fundal variceal bleeding in the antibiotic vs nonantibiotic group

Parameters	Antibiotic group	Non-antibiotic group	P value
	(n = 23)	(n = 19)
Sex ratio (F/M)	5/18	8/11	0.1925
Mean age (yr)	64.4 ± 13.07	65.47 ± 9.83	0.7673
History
Smoking (presence/absence)	12/11	9/10	1
Alcohol (presence/absence)	12/11	8/11	0.5512
Disease conditions
Child-Pugh classification (A/B/C)	2/13/8	2/7/10	NA
Hepatocellular carcinoma (presence/absence)	7/16	7/12	0.7483
Hepatic encephalopathy (presence/absence)	1/22	5/14	0.0754
Form of gastric fundal varices ( F2-F3/F1)	21/2	17/2	1
Concurrent esophageal varices (presence/absence)	17/6	13/6	0.7422
Previous treatment of GV (presence/absence)	0/23	1/18	0.4524
Etiology of liver cirrhosis
Non-viral/viral	9/14	10/9	0.5347
Treatment of gastric fundal varices
Success of initial treatment (success/failure)	22/1	17/2	0.5813
Antibiotics (presence/absence)	23/0	0/19	< 0.0001a
Blood transfusion (presence/absence)	22/1	16/3	0.3129
Medications before admission
NSAIDs (presence/absence)	2/21	3/16	0.6440
Anticoagulant (presence/absence)	0/23	1/18	0.4524
Proton pump inhibitors (presence/absence)	8/15	6/13	1
Blood test results
Hemoglobin (g/dL)	8.97 ± 1.99	8.30 ± 1.63	0.2472
Albumin (g/dL)	2.56 ± 0.47	2.50 ± 0.39	0.6125
Bilirubin (mg/dL)	1.89 ± 1.41	2.09 ± 1.49	0.6616

Antibiotic group: patients with gastric fundal variceal (GFV) bleeding who were administered prophylactic antibiotics; Nonantibiotic group: patients with GFV bleeding patients who did not receive antibiotics.

^aP < 0.05. NA: Not applicable; GV: Gastric varices; NSAIDs: Nonsteroidal anti-inflammatory drugs.