Genetic polymorphisms of MAFK, encoding a small Maf protein, are associated with susceptibility to ulcerative colitis in Japan

Table 3 Association between MAFK polymorphisms and ulcerative colitis

	Genotype (n)			AA vs others		Genotype (n)			CC vs others		Genotype (n)			TT vs others
	GG	GA	AA	OR (95%CI); P value		TT	TC	CC	OR (95%CI); P value		CC	CT	TT	OR (95%CI); P value
rs4268033 G>A
Controls (748)	366	324	58	Reference	-
IBM controls (358)	184	156	18	0.682 (0.402-1.16); P = 0.16	Reference
UC cases (226)	101	89	36	2.63 (1.61-4.30); P = 0.0001	3.54 (1.82-6.88); P = 0.0002
rs3735656 T>C
Controls (748)						329	346	73	Reference	-
IBM controls (358)						168	162	28	0.789 (0.503-1.24); P = 0.30	Reference
UC cases (174)						103	90	33	1.81 (1.12-2.94); P = 0.015	2.14 (1.16-3.95); P = 0.015
rs10226620 C>T
Controls (748)											345	328	75	Reference	-
IBM controls (358)											171	159	28	0.764 (0.488-1.20); P = 0.24	Reference
UC cases (174)											104	94	28	1.37 (0.822 - 2.28); P = 0.23	1.57 (0.827 - 3.00); P = 0.17

UC: Ulcerative colitis.