Management and outcome of hepatocellular adenoma with massive bleeding at presentation

Table 1 Clinical features at presentation

Case no.	Age (yr)	OC use	Type of bleeding, grade	Initial management	ICU	Blood products	Hospital stay (d)	Short-term complications
Initially conservatively treated
1	49	Yes	II	Cons.	No	No	19	-
2	43	Yes	III	Cons.	Yes	Yes	7	-
3	30	Yes	II	Cons.	No	No	7	-
4	36	No	II	Cons.	No	No	19	-
		Stopped 12 mo prior to bleeding
5	33	Yes	II	Cons.	No	No	8	-
6	23	Yes	II	Cons.	Yes	Yes	28	-
7	30	Yes	II	Cons.	No	No	12	-
8	39	Yes	II	Cons.	No	No	9	-
9	43	Yes	III	Cons.	No	Yes	14	-
10	44	Yes	II	Cons.	No	No	13	-
11	49	Yes	III	Cons.	Yes	Yes	61	Hypovolemic shock, respiratory insufficiency, kidney failure, abdominal compartment syndrome
12	31	Yes	II	Cons.	No	No	10	-
13	33	Yes	III	Cons.	No	No	13	-
Initially treated with intervention
14	22	Unknown	III	SAE + resection	No	Yes	40	Postoperative abdominal abscess, drainage pleural effusion
15	33	No	III	SAE	Yes	Yes	Unknown	-
		Stopped 18 mo prior to bleeding
16	24	Yes	III	SAE	Yes	Yes	18	-
17	36	Yes	II	SAE	Yes	No	22	Acute liver failure after SAE left and right hepatic artery
18	48	Yes	II	SAE	No	No	10	-
19	48	Yes	III	SAE	Yes	No	6	-
20	34	No	Unknown	SAE	Unknown	Unknown	Unknown	-
		Stopped 7 mo prior to bleeding
21	30	Yes	II	US-guided drainage	No	No	10	-
22	56	Yes	II	SAE	Yes	No	Unknown	-
23	20	Yes	III	SAE	No	Yes	33	Rebleed after 3 mo, drainage hepatic abscess, drainage pleural effusion

ICU: Intensive care unit; OC: Oral contraceptive; SAE: Selective arterial embolization; US: Ultrasound.